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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOSIP All Species: 25.76
Human Site: Y221 Identified Species: 51.52
UniProt: Q9Y314 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y314 NP_057037.1 301 33172 Y221 L I T R S E R Y V C A V T R D
Chimpanzee Pan troglodytes XP_512823 301 33108 Y221 L I T R S E R Y V C A V T R D
Rhesus Macaque Macaca mulatta XP_001115348 301 33124 Y221 L I T R S E R Y V C A V T R D
Dog Lupus familis XP_541493 313 34339 Y233 L I T R S E R Y V C A V T R D
Cat Felis silvestris
Mouse Mus musculus Q9D6T0 301 33190 Y221 L I T R S E R Y V C A V T R D
Rat Rattus norvegicus NP_001099730 301 33239 Y221 L I T R S E R Y V C A V T R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NUH3 298 33285 A221 R Q D R Y V C A V T R D M L G
Zebra Danio Brachydanio rerio Q5U3S7 304 33314 Q221 R V A L L T R Q D R Y V C A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VWV8 307 34139 Y227 L I A K E A R Y M C P I T H D
Honey Bee Apis mellifera XP_001120134 289 32503 P212 K Q A R Y M C P I T H D I L S
Nematode Worm Caenorhab. elegans Q21755 310 33954 G221 V K F T P M P G T E T A A H R
Sea Urchin Strong. purpuratus XP_790354 297 33332 A220 K R E R Y K C A V T H D V L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 99.3 88.8 N.A. 90.6 91.6 N.A. N.A. N.A. 70.7 65.1 N.A. 49.8 53.1 43.8 52.4
Protein Similarity: 100 99.6 99.6 91.6 N.A. 93.3 93.3 N.A. N.A. N.A. 85.3 80.5 N.A. 66.1 70 61.2 69.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 13.3 N.A. 46.6 6.6 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 20 N.A. 66.6 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 0 0 9 0 17 0 0 50 9 9 9 0 % A
% Cys: 0 0 0 0 0 0 25 0 0 59 0 0 9 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 0 0 25 0 0 59 % D
% Glu: 0 0 9 0 9 50 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 17 0 % H
% Ile: 0 59 0 0 0 0 0 0 9 0 0 9 9 0 0 % I
% Lys: 17 9 0 9 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 59 0 0 9 9 0 0 0 0 0 0 0 0 25 0 % L
% Met: 0 0 0 0 0 17 0 0 9 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 9 9 0 0 9 0 0 0 0 % P
% Gln: 0 17 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 17 9 0 75 0 0 67 0 0 9 9 0 0 50 9 % R
% Ser: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 17 % S
% Thr: 0 0 50 9 0 9 0 0 9 25 9 0 59 0 0 % T
% Val: 9 9 0 0 0 9 0 0 67 0 0 59 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 25 0 0 59 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _